Medications for the treatment of HIV - Updated June, 2008
It should be understood that only a small percentage of people suffer debilitating side effects, and in most cases the side effects can be controlled if they know in advance what to expect if they should they occur. For information on where and how these medications work see T.A.S.K. lesson 2. For tips on managing side effects and adherence see T.A.S.K. lesson 3.

Protease Inhibitors (PI)

Patient Assistance Programs are available for those who cannot afford the medication, do not have insurance and cannot qualify for other assistance programs. Click on "Finances" for more information on these programs.

All of these medications, with the possible exception of un-boosted Reyataz, can cause elevated lipid (fats) levels - higher than normal triglycerides and cholesterol; this is called hyper-lipidemia. They may also worsening or cause new cases of diabetes, cause loss of fat (lipoatrophy), and possible increased bleeding in hemophiliacs
Medication
Name
Usual Adult Dose
Possible Side Effects
Manufacturer & Patient Assistance Program information

Aptivus tipranavir

Two 250mg capsules with two 100mg capsules of Norvir twice a day (bid); taken with food
Hyper-lipidemia (see above), mild diarrhea, nausea, vomiting, fatigue, headaches, dry mouth, rash, dizziness, and possible liver toxicity and bleeding in the brain. Aptivus contains "sulfa" based drugs so caution should be used when prescribed to patients allergic to sulfa drugs.

Boehringer Ingelheim Pharmaceuticals, Inc. www.RxHope.com.

1-800-556-8317

Crixivan indinavir

Two 400mg capsules every 8 hours. Usually boosted with Norvir. Take on empty stomach except when taken with Norvir
Hyper-lipidemia (see above), nausea, headache, diarrhea, vomiting, gas, cramps, weakness, loss of appetite, loss of body fat, particularly noticeable in face (lipoatrophy), dry mouth, dry skin, change in taste, liver toxicity, yellowing of skin and eyes (jaundice), joint pain and hives, kidney stones (drink plenty of water to avoid this)

Merck

SUPPORT TM - PO Box 222137
Charlotte, NC 28222-2137
Fax:1-704-357-0036 Phone: 1-800-850-3430

http://www.crixivan.com/ indinavir_sulfate/crixivan/ consumer/support/index.jsp

Invirase saquinavir
Two 500mg tablets and one 100mg Norvir caplet; take with food
Hyper-lipidemia (see above), nausea, diarrhea, vomiting, gas, cramps

Roche

Roche Patient Assistance Foundation

1-877-75ROCHE (877-757-6243)

Kaletra

lopinavir & ritonavir

Four tablets(200mg lopinavir & 50mg of ritonavir [Norvir]); with or without food
Hyper-lipidemia (see above), nausea, headache, diarrhea, vomiting, gas, cramps, swollen abdomen, weakness, possible liver toxicity

Abbott

Pharmaceutical Research and Manufacturers of America (PhRMA)

Partnership for Prescription Assistance (PPA)

1-888-4PPA-NOW (1-888-477-2669)

https://www.pparx.org/Intro.php

Lexiva

fos-amprenavir calcium

Two 700mg tablets with 200mg caplet of Norvir once a day, or twice a day if PI experienced; with or without food
Hyper-lipidemia (see above), mild diarrhea, nausea, vomiting, fatigue, headaches, mouth numbness, rash, mood disorders Lexiva contains "sulfa" based drugs so caution should be used when prescribed to patients allergic to sulfa drugs.

GlaxoSmithKline (GSK)

http://www.gskforyou.com/

1-866-GSK-FOR-U,
(1-866-475-3678)

Norvir ritonavir
This medication is now used primarily to boost, or enhance other Protease Inhibitors; taken with food when possible
Hyper-lipidemia (see above), nausea, headache, diarrhea, vomiting, gas, cramps, swollen abdomen, weakness, loss of appetite, weight loss, tingling and numbness around mouth, change in taste, dizziness, pancreatitis, liver toxicity, muscle pain and high uric acid

Abbott

Pharmaceutical Research and

Manufacturers of America (PhRMA)

Partnership for Prescription Assistance (PPA)

1-888-4PPA-NOW (1-888-477-2669)

https://www.pparx.org/Intro.php

Prezista darunavir
Two 300mg tablets with 100mg of Norvir twice a day; taken with food
Hyper-lipidemia (see above), mild diarrhea, nausea, headaches, dry mouth, and symptoms of a common cold. Prezista contains "sulfa" based drugs so caution should be used when prescribed to patients allergic to sulfa drugs.

Tibotec Therapeutics

Phone: 1-866-836-0114

Fax: 1-800-836-0567

http://www.prezista.com/

patient_assistance.html

Reyataz atazanavir sulfate
One 300mg capsule with 100mg of Norvir, or two 200mg capsules once a day as prescribed; taken with food
Possible liver toxicity, dizziness and lightheaded feeling

Bristol-Myers Squibb

http://www.bmspaf.org/

1-800-736-0003

Viracept nelfinavir
two 625mg tablets twice a day; taken with food
Hyper-lipidemia (see above), nausea, headache, diarrhea, vomiting, gas, cramps, swollen abdomen, weakness and rash

Pfizer

https://www.pfizer helpfulanswers.com/ pages/misc/Default.aspx

1-866-776-3700