Medications for the treatment of HIV - Updated July, 2008
It should be understood that only a small percentage of people suffer debilitating side effects, and in most cases the side effects can be controlled if they know in advance what to expect if they should they occur. For information on where and how these medications work see T.A.S.K. lesson 2. For tips on managing side effects and adherence see T.A.S.K. lesson 3.

Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTI)

Expanded Access means that the medication is in the final stages of approval by the FDA and is available to those failing on current medications. Your doctor or case manager can contact the company and enroll you it the Expanded Access Program. Expanded Access Programs stop taking new patients when medications are approved; however, they may be available through Patient Assistance Programs, once approved, for those who cannot afford the medication, do not have insurance and cannot qualify for other assistance programs. Click on "Finances" for more information on these programs.

Medication
Name
Usual Adult Dose
Possible Side Effects
Manufacturer & Patient Assistance Program information

Rescriptor delavirdine

Two 200mg, or four 100mg tablets, three times a day (tid): with or with food
Hypersensitivity reaction - rash and itchy skin, nausea, vomiting, diarrhea, fatigue, headache, fever, elevated liver enzymes. This drug is seldom used today when medications with fewer side effects are available.

Sustiva efavirenz

One 600mg tablet, or Three 200mg capsules, once a day (qd); on empty stomach
Central nervous system (CNS, a feeling of intoxication, drowsiness), anxiety, depression, trouble sleeping, hypersensitivity reaction - rash and itchy skin, nausea, vomiting, diarrhea, fatigue, headache, fever, elevated liver enzymes, cholesterol and triglycerides

Bristol-Myers Squibb http://www.bmspaf.org/

1-800-736-0003

Intelence Entravirine TMC125

 

Two 100mg tablets, taken with food twice a day (bid)
Hypersensitivity reaction - severe rash and itchy skin (report to doctor immediately), mild rash that usually appears one to two weeks after starting but then goes away, nausea, vomiting, diarrhea, fatigue, headache, high blood pressure, abdominal pain, peripheral neuropathy (pain, tingling or numbness in hands and feet/legs)

Online submission of assistance form available at www.Tibotec_TherapeuticsLine.com

1866-836-0114

Viramune nevirapine
Start with one 200mg tablet once a day for the first 14 days, then one 200mg tablet twice a day; with or without food
Hypersensitivity reaction - rash and itchy skin, nausea, vomiting, diarrhea, fatigue, headache, fever, elevated liver enzymes possibly to the point of drug induced hepatitis

Boehringer Ingelheim Pharmaceuticals, Inc. www.RxHope.com.

1-800-556-8317